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Thyroidectomy is generally the preferred option in the following settings: moderate-to-severe Graves orbitopathy women who desire a pregnancy within the next 612 months large goitres causing compressive symptoms or goitres with significant retrosternal extension where thyroid malignancy is suspected when patients are fearful of taking radioactive medication

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After curing, the slices were cut into 5-m slices with a microtome, which were pasted on a slip-proof slide to prepare specimens for baking at 65C for 1 h

In recent years, the influence of epigenetic modifications on NRF2 has gained increasing attention, highlighting their significance in the broader context of cellular stress responses and disease progression [144,145,146]

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